dedicated citrullin 300g

For supporting athletic performance, citrulline malate, a combination of L-citrulline and malate, is generally recommended. The recommended daily dose of citrulline malate is between 6 and 8 grams per dose. Beginners are advised to start with 4-6 grams to test their individual tolerance.
When taking pure L-citrulline, the optimal dose is 3-6 grams per day.
Ideally, it should be taken about 30-60 minutes before training to maximize its effect at the time of exertion. Since citrulline malate does not require "loading," taking it only once on training days is sufficient. To observe the positive effects on blood flow, performance enhancement, and delayed fatigue, it is advisable to take citrulline over a longer period. There is no evidence of serious side effects at the recommended dosage; however, mild gastrointestinal discomfort may occur at very high doses (over 10 g).

Taking L-citrulline is more effective at increasing blood arginine levels than directly supplementing with L-arginine because L-citrulline has significantly higher bioavailability.

When L-arginine is taken orally, it undergoes a strong first-pass effect. A large portion of the amino acid is broken down in the small intestine and liver by the enzyme arginase before it can reach the systemic bloodstream. This severely limits the amount of arginine available for nitric oxide synthesis.

L-citrulline, on the other hand, is hardly metabolized in the intestine and liver. It passes through these organs almost completely and is then efficiently converted into L-arginine in the kidneys. Scientific studies have shown that L-citrulline supplementation leads to higher and more stable arginine levels in blood plasma over a longer period than taking the same amount of pure L-arginine. Furthermore, L-citrulline is usually better tolerated at higher doses, as it less frequently leads to the gastrointestinal problems typical of arginine.

The optimal time to take Dedicated Citrulline is approximately 30 to 60 minutes before training, as the body needs this time to effectively metabolize the amino acid and increase nitric oxide production for improved blood flow. Combining it with other NO-boosting supplements or pre-workout boosters to maximize the pump effect is perfectly acceptable and common practice among many athletes, as the various mechanisms of action often complement each other synergistically. However, care should be taken to check the ingredients of the combined booster to avoid unnecessary overdosing if it already contains significant amounts of citrulline.

Yes, taking it on rest days is beneficial to ensure consistently optimized nitric oxide production in the body. For optimal effect, it is recommended to distribute the daily dose evenly throughout the day, for example, in the morning, at midday, and in the evening.